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I'm not aware of any guideline stating that non-slit septa are a must in an regulated environment. And I don't know why the state of the HPLC is
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PTFE/Silicone septa (T/S) are the most useful for HPLC applications as they have wide chemical compatibility and low extractables (I recommend them for general
We have currently a similar problem for an HPLC method (Alliance). We observed that the control standards were always negative, and that they
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PTFE/Synthetic red rubber septa are an economical choice for general GC and HPLC applications. Used primarily for routine analysis in gas chromatography with
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